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Semaglutide binds to and activates GLP-1 receptors in various tissues, including the pancreas, brain, and gastrointestinal tract

4 For example, ADA and KDIGO joint group has recommended that for patients with T2DM and CKD who do not achieve their glycemic target with metformin and/or an SGLT2i or cannot use them, a GLP-1RAs with proven cardiovascular benefit is recommended

If they have questions or need clarification, they may reach out through the platforms messaging system before finalizing the prescription

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