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The safety data available derive from Phase 2 clinical trials (Jastreboff et al., NEJM, 2023), which, whilst informative, represent a relatively limited population and duration of follow-up compared to post-marketing surveillance

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For instance, you may have metabolic syndrome or cardiovascular risk factors like high triglycerides and elevated blood pressure that havent responded to lifestyle changes alone

For peptide-based fat loss researchers, metformin often serves as a foundational complement rather than a standalone solution

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