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Diagnostic approach ABCDE survey Targeted clinical evaluation 12-lead ECG CBC: Initial Hb/Hct may not reflect the degree of acute hemorrhage

FDA has agreed to the primary endpoint expected to be utilized in Phase 3 - Data from two Phase 2 studies of avexitide in people with PBH demonstrated highly statistically significant reductions in severe hypoglycemic events, an endpoint supported by the FDA - Avexitide was generally well tolerated, with a favorable safety profile replicated across five clinical trials in people with PBH - Management to host conference call and webcast today at