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In crude analyses, GLP-1 receptor agonist use was associated with an increased incidence of suicidality compared with DPP-4 inhibitors (crude incidence rates 3.9 v 1.8 per 1000 person years, respectively

Trial registration www.anzctr.org.au ACTRN12621000878875 Funding The study was not funded by a specific research grant

In patients with diabetes mellitus not achieving targets on lifestyle measures, pharmacologic therapy should be considered

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