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At 12 months, patients receiving exenatide had a mean improvement of 2.7 points, while the control group had a mean decline of 2.2 points, indicating a statistically significant difference of 4.9 points (95% CI, 0.3-9.4
By week 12 of the experimental treatment period, the patients administered doses of semaglutide from 0.8-1.6 mg experienced a decrease in weight ranging from -3.4 to -4.8 kg
In its Complete Response Letter, the regulator cited deficiencies in the companys clinical application
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