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High-risk groups include older adults, vegans, metformin users, those on long-term PPIs, and patients with a history of gastrointestinal surgery
You may notice changes in appetite, energy, sleep, or menstrual cycles, and ask, does semaglutide affect hormones
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It's the confidence of knowing you have a dedicated clinical team guiding you, ensuring the plan is working and adjusting it as needed
The 5-day half-life makes once-weekly dosing pharmacokinetically optimal: the 7-day dosing interval is long enough that levels don't accumulate to dangerous heights, yet short enough that trough concentrations remain therapeutically active throughout
