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The GLP-1 receptor/GIP receptor/GCGR triple agonist efocipegtrutide is presently under investigation in individuals with MASLD, and preclinical accounts of other dual and triple agonists that include GLP-1 receptor and GCGR agonism suggest that clinical studies in individuals with type 2 diabetes will follow [62, 63]
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Additionally, Goldman Sachs projects the broader market for anti-obesity drugs including Zepbound could to hit $100 billion per year by 2030, a 16-fold increase from 2023 levels
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Also, specific mechanisms underlying these effects need better elucidation
