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Early treatment with antibiotics can prevent progression to pyelonephritis (kidney infection) and serious complications

Moreover, although some studies indicate that GLP-1RAs can rescue diabetic vascular endothelial damage via suppressing STING signaling [27], it remains unclear whether they exert an intervention effect in delaying RA progression by targeting the underlying cGAS-STING-ferroptosis pathway

Finally, concerns regarding the use of tri-agonism in patients have centered around the potential of GCGR agonism to elevate heart rate, in addition to its effects on increasing energy expenditure (Petersen et al

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