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Randomized 1:1:1 to retatrutide 9 mg, retatrutide 12 mg, or placebo for 68 weeks

A nourishing diet coupled with resistance training is central to such approaches, as dietary protein stimulates muscle protein synthesis

Pricing, convenience, and scale drive competition While Amazons pricing is broadly in line with existing offerings, its competitive edge lies in logistics and accessibility

While some people notice a decrease in appetite within the first week, significant weight loss usually becomes more apparent as you reach the 1.0 mg dose and beyond (around Month 3)

Third, missing data were handled through multiple imputation, which can potentially introduce bias because there may be differences between the participants for whom data are imputed and those used for the imputation