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Associations with fracture in patients with diabetes: a nested case-control study

History of bowel obstruction or ileus Slowed motility may increase risk in susceptible individuals

Starting at lower doses and increasing according to product-specific schedules (ranging from 1-4 weeks depending on the agent) allows physiologic adaptation

For perimenopause and menopause Up to 85% of women experience menopause-related symptoms, including weight redistribution, fatigue, mood changes, and joint pain

GLP-1 agents, while costly and not yet guideline-endorsed for prevention, offer broader metabolic benefits without inherent bleeding risk