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Vasodilation is achieved by activating endothelial nitric oxide synthase (eNOS) and increasing nitric oxide (NO) production via the cAMP/PKA, AMPK, and PI 3 K/Akt signaling pathways [17]

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Author contributions GM had the idea for the article, GM, MP, MEG, SB, VG performed the literature search, GM, MEG, SB, VG drafted and critically revised the work, LB, AC, WY, PS critically revised the work

Upregulated NLRP3 inflammasome in patients with type 2 diabetes

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