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Methods: This review synthesizes data from 1565 clinical trials (Phases IIV) sourced from the Trialtrove database (November 2024), covering nine GLP-1RAs: mono-agonists (beinaglutide, liraglutide, semaglutide, orforglipron), dual agonists (tirzepatide, mazdutide, survodutide, cagrilintide), and the triple agonist retatrutide
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