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We denote this end of the trajectory as the most like. The -3, -4, and -5 subclusters were at the other end of the pseudotime trajectory, exhibiting the highest expression of MAFA and PDX1 , suggesting that these subpopulations were the most mature cell subpopulations
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These data suggest that GLP-1RAs may become a promising strategy for the prevention of cognitive impairment associated with obstructive sleep apnea [68] and in other situations associated with brain hypoxia

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