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Jansen et al
Beyond glucose control and weight loss, benefits like a reduction in the risk of stroke, heart attacks, major cardiac events and kidney disease were expected, since some GLP-1 medicines have already been shown to be beneficial in reducing the incidence of these disorders in people with type 2 diabetes in clinical trials
Roche with its 2024 acquisition of Carmot, and Pfizer, following its 2025 acquisition of Metsera, enter obesity and broaden their presence in cardiovascular/metabolic, while other large pharmaceutical companies prepare to follow later in the decade
Dietary fat, sugar consumption, and cardiorespiratory fitness in patients with heart failure with preserved ejection fraction
Alcohol also contains empty calories and can contribute to dehydration
