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When plaque burden is high, especially in the setting of elevated Lp(a), preventive therapy becomes far more intentional

GLP-1 medications delay gastric emptying, meaning stomach contents may remain present longer than expected even after appropriate fasting

However, starting a GLP-1 medication before thyroid levels are stable can mask symptoms and make it harder to find your correct thyroid dose
The hyperglycaemia buffer of dual-incretin action is a particularly important benefit as it allows for more potent development of the glucagon constituent in drug formulation in order to promote greater weight loss [90]

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