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Time-to-event (TTE) endpoints have been successfully used in trials for other neurodegenerative diseases, including multiple sclerosis 10 , amyotrophic lateral sclerosis 11,12 and Alzheimers disease 13,14,15 , and may offer a promising way to measure disease progression in clinical trials for PD

However, it should be used alongside lifestyle interventions

It blocks an enzyme called PDE5

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This dual action slows down stomach emptying, reduces feelings of hunger, increases calorie burning, and improves insulin sensitivity, resulting in significant weight loss