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P.GalliA.et al (2020)

In the SURPASS and SURMOUNT trials, Lilly has so far compared tirzepatide to older treatments or placebo (for T2D and obesity)

But much of what gets reported as lean mass loss has not been proven to be skeletal muscle loss

May have higher risk of GI or metabolic side effects

doi: 10.1016/j.amjcard.2011.03.046
