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In this study, 4076 patients living with T2DM and either a history of CVD (90%) or kidney disease and at least one other cardiovascular risk factor were randomized to receive once-weekly 4 mg or 6 mg efpeglenatide injection or placebo (median follow-up 1.81 years)

Ozempic comes with a black box warning, the FDAs highest safety warning, for the possible development of medullary thyroid cancer and multiple endocrine neoplasia syndrome type 2 (MEN-2)

Miracles up to a point

In the same FDA drug safety communication, post-marketing cases of urosepsis and pyelonephritis were discussed, leading to the addition of warnings of severe infections to the prescribing information for these products

In 2026, access is not a secondary consideration in GLP-1 therapy