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NICE guidance emphasises individualised glycaemic targets, particularly when multiple medications affecting glucose metabolism are used concurrently

Potential Side Effects While most patients tolerate Semaglutide well, mild side effects may occur during the adjustment period, including: Nausea Stomach cramping Indigestion or constipation Loose stool Mild redness or discomfort at the injection site These effects are typically temporary and can often be managed with over-the-counter remedies

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Manufacturer copay cards and patient assistance programs exclude uninsured self-pay patients by design

It represents the next generation beyond dual agonists like tirzepatide