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Additional experimental data support the protective role of GLP-1, including improved outcomes in DPP-4 knockout rats exposed to endotoxins and reduced mortality following GLP-1R activation (Perl et al., 2018

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High risk of fractures within 7 years of diagnosis in Asian patients with inflammatory bowel diseases

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3.4 Appetite regulation and weight management Similar to animal studies with deletion of the GIPR gene that exhibit protection toward obesity (53), early genome-wide association studies (GWAS) in humans have revealed the GIPR gene to be associated with BMI (103)

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