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If a patient develops severe joint pain discontinue the DPP-4 inhibitor

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Who Should Avoid GLP-1 Medications Genetic and Cancer Concerns If you or your family has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia type 2 (MEN 2), GLP-1 medications come with an increased risk of thyroid C-cell tumors and should be avoided