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Patients should also be advised to discontinue therapy in case of severe vomiting or diarrhea

The study included 26 women with PCOS who were overweight or obese and had insulin resistance

"SNAC-enabled oral peptide delivery: absorption mechanisms and clinical implications." Clinical Pharmacology in Drug Development

Jena, MD PhD Department of Health Care Policy, Harvard Medical School , Boston, MA Department of Medicine, Massachusetts General Hospital , Boston, MA National Bureau of Economic Research , Cambridge, MA, Nicholas Stucky, MD PhD Truveta, Inc , Bellevue, WA With the growing popularity of GLP-1 RAs, concerns have been raised that the expanded use may occur amongst patients with less clinical need