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The tricky part is that mild degradation produces no visible changes

For Novo Nordisks Wegovy pill, study participants achieved an average weight loss of 13.6 percent by 16 months

Phase 2 clinical trial A phase 2, randomised, double-blind, placebo-controlled trial involving 338 adults with obesity or overweight (BMI 30 or BMI 27 with at least one weight-related condition) provides strong evidence for retatrutides efficacy

doi: 10.1136/bmj.g7607

Thats why avoiding foods that trigger heartburn, such as spicy foods, can help ease symptoms
