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Semaglutide binds to blood proteins and pools in subcutaneous tissue, so the effective pace at which it leaves you depends on how fast it moves out of those reservoirs, not just the single-number half-life printed on a label

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The timing of your GLP-1 injection plays a meaningful role in how your body responds to treatment

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Measurable weight loss usually becomes apparent after 46 weeks, with most patients experiencing their fastest weight loss between weeks 816 as their dose reaches therapeutic levels

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