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Description
In this large, propensity-matched, cohort study, individuals with obesity treated with tirzepatide were significantly more likely to achieve clinically meaningful weight loss and larger reductions in body weight compared with those treated with semaglutide, wrote first author Patricia J

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This is particularly relevant during the initial weeks of treatment when gastrointestinal side effects are most pronounced
Men lose weight faster in absolute terms early in treatment but show more variable long-term maintenance
