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Description
Wegovy, another Novo Nordisk drug with semaglutide, is prescribed to help obese people lose weight and to reduce the risk of major cardiovascular events in obese or overweight adults with known heart disease

AMPK antagonizes mammalian target of rapamycin (mTOR) activity, and its downstream effector, p27, inhibits cyclin-dependent kinase 2 (CDK2), thereby blocking the G1/S transition in the cell cycle, halting cell division, and subsequently inhibiting cellular proliferation [57]

Because the stomach empties more slowly on these drugs, it can make it easier to vomit up food, says Keel

It requires you to do some work beyond medication

For a lupus patient whose hsCRP runs chronically elevated, this kind of reduction could meaningfully affect disease trajectory
