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GLP-1 .131 , - GLP-1R .131 GLP-1R GLP-1 - .247 , .244 , - GLP-1R .248 GLP-1 - .248 - - .249,250 - GLP-1R GLP-1 .248,251,252 T2DM GLP-1 (: GLP-1RAs)

The ominous octet, which includes 8 key pathophysiologic defects found to be present in T2D, is illustrated in Figure 1

Healthy Fat Inclusion Prioritize quality sources: olive oil, avocado, nuts, seeds, and fatty fish

Interestingly, confirming the key role of intestinal barrier damage in metabolic disease, positive results come from the use of Lubiprostone (LUB) in NAFLD: it is a bicyclic fatty acid, usually used in constipation, which has the ability to promote intestinal fluid secretion

The types of hair loss documented included telogen effluvium (the most common), androgenic alopecia, and alopecia areata