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Regular exercise helps to lose fat, particularly around problem areas like love handles, by creating a calorie deficit

In the ATTAIN obesity trials, maintenance doses of 6 mg, 12 mg, and 36 mg were evaluated, with 36 mg producing the greatest weight loss

In the SURMOUNT-1 trial, tirzepatide achieved up to 22.5% body weight reduction over 72 weeks, compared to roughly 17% with semaglutide in similar studies

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