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The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation
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A plausible explanation for the apparent advantage of GLP-1 RAs may involve their superior weight-loss efficacy relative to other antidiabetic drugs, particularly SGLT-2is, which themselves confer substantial CV benefits

GLP-1 medications in the refrigerator will remain within safe temperature range for that same window

Glycemic control in patients with type 2 diabetes mellitus switched from twice-daily immediate-release metformin to a once-daily extended-release formulation
