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It also acts on the brain to reduce appetite and food intake, leading to weight loss

To date, all CVOTs for dipeptidyl peptidase 4 (DPP-4) inhibitors, 4-7 glucagon-like peptide-1 receptor agonists (GLP-1 RAs), 8-13 and sodium-glucose transport protein 2 (SGLT-2) inhibitors 14-16 have documented a lack of increased CV risk (non-inferiority) with the investigational product in patients with T2DM compared to placebo

More than two in five adults in the U.S

Patients with a history of pancreatitis should use caution, and those with severe gastrointestinal disease (such as gastroparesis) may not tolerate the medication well due to its effects on gastric emptying

These cases are consolidated in MDL No