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Nutrient sensing: LEAP2 concentration in response to fasting, glucose, lactate, and beta-hydroxybutyrate in healthy young males

Your baseline metabolic ratethe calories your body burns at restdoesn't change significantly on semaglutide, but your total daily energy expenditure drops because you eat less and move less if appetite suppression is severe
Proper dosing, monitoring, and medical oversight are essential for both the safety and effectiveness of semaglutide injections

Often, yes, GLP-1s may be safer for patients unfit for anesthesia or major surgery, though risks like nausea and long-term dependence remain.

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