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Sensitivity analyses of the dual primary, confirmatory secondary, select supportive secondary, and exploratory endpoints that were additionally adjusted for baseline LVEF, NYHA functional class, NT-proBNP, and diuretic use produced results that were similar to the main analyses (Supplemental Table 1)

Future research will expand beyond Reddit and include non-English communities to determine whether similar trends appear in other populations

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This likely reflects dose differences rather than efficacy differences, but it definitively disproves the myth that diabetes is required for weight loss response