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however, this contradicts established trial data favoring SGLT2 inhibitors for heart failure and should be interpreted cautiously due to possible residual confounding
In crude analyses, GLP-1 receptor agonist use was associated with an increased incidence of suicidality compared with DPP-4 inhibitors (crude incidence rates 3.9 v 1.8 per 1000 person years, respectively
A number of investigational new drugs targeting GLP-1R, GIPR and GDF-8 pathways are under clinical trials (Table 2)
Healthon connects patients with U
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