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Eli Lilly, makers of weight loss injection Zepbound, could soon be making its GLP-1 drug in pill form.

FDA-approved semaglutide products (Ozempic, Wegovy, Rybelsus) are commercially available

Purpose of Review This review will summarize the most contemporary trials for glucagon-like peptide 1 receptor agonists (GLP1-RA) and sodium-glucose cotransporter 2 inhibitors (SGLT2-i) and present guidance on management and recommendations on adjunctive tapering of insulin in patients with insulin-dependent diabetes mellitus, which we term de-insulinization. Recent Findings GLP1-RA and SGLT2-i are the principal classes of diabetes medications evidencing cardiovascular benefit

Outcomes included changes in left ventricular ejection fraction (LVEF), end-diastolic volume (LVEDV), end-systolic volume (LVESV), global longitudinal strain (GLS), left ventricular mass, left atrial volume (LAV), and NT-proBNP levels

Whether youve just started therapy or have been on it for a while, this supplement can help alleviate ongoing side effects, support energy, and enhance gut health