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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are commonly used for managing type 2 diabetes and obesity

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When stratified by maximum dose achieved, semaglutide prescribing declined more sharply after the landmark among patients who had reached higher doses than among those who remained in the low-dose group, indicating that more intensive treatment during pre-landmark period did not necessarily translate into sustained exposure in the following post-landmark period (Fig

There's emerging animal research showing that semaglutide modulates dopamine dynamics in the nucleus accumbens, a region involved in reward and motivation