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The second strategy focuses on DPP-4 inhibitors, which prevent the rapid degradation of endogenous GLP-1 by inhibiting the DPP-4 enzyme, thereby extending the hormone's activity

doi:10.1016/j.neuropharm.2018.01.040 33

J Urol 152:10171021

Co-primary: WOMAC pain score reduced by up to 4.5 points (75.8% improvement)

11, 12 While these studies cant prove the drugs prevented dementia, they strongly suggest that GLP-1 drugs provide meaningful protection against cognitive decline
