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9-13 In two of the trials, there was a significant association between the use of a synthetic GLP-1/GIP agonist and worse eye-related outcomes

As doses increase, some side effects may return, but with monitoring and care, they can be managed, he adds

The safety profile of the new drugs also still needs to be improved, as does patient access to the new therapies

Amgens MariTide shows approximately 20 percent weight loss in Phase 2 with durable metabolic improvements, signaling a shift toward monthly or lower frequency dosing models

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