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Dual GIP/GLP-1 agonists, such as tirzepatide, show greater reductions in weight and blood sugar than GLP-1-only medications

Compounded semaglutide is typically appropriate for adults with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol

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While preclinical studies, primarily in animal models 17,18 , suggest a potential beneficial effect of GLP-1 RAs on mood and behavior, the clinical evidence in humans remains unclear 19,20