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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are peptide-derived analogs that were initially investigated to treat type 2 diabetes

Edit to note that the chart does not include older medications such as diethylpropion, phentermine and phendimetrazine (still available) and sibutramine (no longer available)

GLP-1s were created to help treat type 2 diabetes, but now they have shown real promise in helping people lose weight

Everything we know about GLP-1s so far

Significant Clinical Interaction Alert Semaglutidelithiumlevothyroxine interaction A patient on long-term lithium and levothyroxine started semaglutide 0.25mg weekly, filled at a pharmacy without their full medication history on file