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plantarum strains, which is what the clinical trial should clarify
In some cases, significant weight loss and energy deficit can lead to functional hypothalamic amenorrhoea, where the brain temporarily reduces signals to the ovaries

A recent meta-analysis of 14 RCTs in adolescents with overweight or obesity (including those with type 2 diabetes) confirmed that GLP-1 RA therapy led to mean HbA1c reductions (0.34% risk difference) and weight loss (4.3 kg) relative to the control group (34)

Examples of other drugs that may be used for weight loss and weight management include: orlistat (Alli, Xenical) phentermine (Adipex-P, Lomaira) phentermine/topiramate (Qsymia) naltrexone/bupropion (Contrave) semaglutide (Wegovy) When you first start treatment with Saxenda, your doctor will gradually increase your dosage over a few weeks

The peer-reviewed published study: Duncan et al., "Individualized virtual integrative medicine (IVIM): A clinical model for enhanced GLP-1 therapeutic outcomes," Obesity Pillars , 2025 (PubMed indexed)
