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Always follow the manufacturer's recommended titration schedule in the SmPC, and consider extending the time at lower doses if patients experience significant gastrointestinal symptoms

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We dont know if semaglutide will become an all-purpose tool for a wide range of addictive behaviors, but we agree with the investigators that larger clinical trials would be appropriate

The GIP component enhances insulin secretion and may improve fat metabolism

Radiolabeled exendin-4 derivatives, such as 68 Ga-NOTA-exendin-4 and 18 F-PEG-exendin-4, have significantly enhanced the sensitivity and specificity of insulinoma detection via PET/CT, outperforming conventional imaging modalities [346350]