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This state-of-the-art narrative review synthesizes current evidence from clinical trials, pharmacovigilance databases, and real-world cohorts to provide a comprehensive evaluation of the safety and tolerability of GLP-1RAs and tirzepatide

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GLP-1 medications are available through multiple channelsbranded pharmaceuticals, online telehealth platforms, and licensed compounding pharmacies

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They work by mimicking the effects of the naturally occurring hormone called glucagon-like peptide-1 (GLP-1), which is responsible for regulating insulin and blood sugar levels