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Glucagon-like peptide-1 (GLP-1) receptor agonists and their cardiovascular benefits-the role of the GLP-1 receptor

& Abu-Raghif, A

Using fusion proteins of wild-type and mutant GLP-1R C-terminal tails, in vitro phosphorylation experiments revealed that PKC-mediated phosphorylation occurred predominantly at residues 431/432, and, whereas positions 444/445 and 451/452 could be phosphorylated by PKC, they were poor substrates

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Dose Range: 0.252.4 mg weekly