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3 If initial therapy with metformin and lifestyle efforts are not adequate to achieve individualized glycemic targets, the guidelines recommend that patients should progress to dual therapy by adding either another oral agent, basal insulin, or an injectable GLP-1 receptor agonist

Available from: Xiao P, Wang H, Liu H, Yuan H, Guo C, Feng Y, et al
Horm Mol Biol Clin Investig

Evidence indicates that GLP-1RAs confer substantial cardiovascular and renal benefits

Chen BD, Zhao WC, Dong JD, Sima H
