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The most consistent risk factor, however, is a small cup-to-disc ratio, referred to as a disc at risk, characterized by crowding of the optic nerve head with a resultant compartment-like syndrome of the nerve [36]
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For example, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), and peptide YY (PYY) are anorexigenic gut hormones that inhibit appetite
