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Gastrointestinal side effects like diarrhea affect up to 20% of semaglutide users during the first weeks of treatment
Importantly, increasing the endogenous production of GLP-1 by different mechanisms or by increasing the number of intestinal L-cells that tend to produce this hormone may be another effective therapeutic approach to managing T2DM

Recent observations and emerging research have raised concerns about increased tendon injuries and declining bone health in some individuals using GLP-1 therapies
These medications have increased in popularity over the past few years, and there is a lot of interest - especially in women who are wanting to lost weight postpartum
