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Blockade of ActRII enhances fat mass loss and preserves lean mass during GLP-1 receptor agonism in obese mice To determine the effects of antibody ActRII blockade (bimagrumab) and GLP-1 receptor agonism (semaglutide) on body composition, 25-week-old diet-induced obese mice (DIO) were obtained and maintained on a high fat diet (60 % kcal from fat)
The New England journal of medicine , 371 (7), 624634
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