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Fewer events in the placebo arm of SURMOUNT-1 compared with ONeil, STEP 1 and STEP 8 for total gastrointestinal AEs and nausea AEs suggest that the relative safety of tirzepatide versus liraglutide and semaglutide may be underestimated for these outcomes (see Supplementary Material Table S3)

We monitor throughout treatment

While many compounders offering GLP-1s are still filling doctors prescriptions, others have stopped offering the drugs because of legal worries, Hemmi said

You can always check sites that offer discounts, like SingleCare and GoodRx

Weight loss tends to improve things like blood sugar, cholesterol, and blood pressure, says Kushner