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It can also reduce the risk of leg cramps

Khan Z et al

If you then inject air to equalize pressure, that air creates a positive gradient that forces solution back through the needle tract during withdrawal

Although it has been approved and prescribed in Spain since 2017, its fame seems to have exploded in recent months, leading to shortages and peoples obsession with getting their hands on the precious injections

Thus, access to the brain parenchyma for peripherally administered GLP1 receptor agonists via the ventricular system seems unlikely, though probably deserves further detailed experimental attention in order to produce an unequivocal answer
