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[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Trujillo, J

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Heres what happens: Grapefruit contains furanocoumarins, a type of organic chemical compound that inhibits the efficacy of an important enzyme, called CYP3A4

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Notably, a 2020 clinical trial involving patients with nonalcoholic steatohepatitis (NASH) revealed a 15% incidence of tumors (benign, malignant, or unspecified) (35/239) among those administered semaglutide, compared to 8% (6/80) in the control group [108]